Chronic Myeloid Leukemia

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Chronic myelogenous leukemia Classifications and external resources The Philadelphia chromosome as seen by metaphase FISH. ICD-10 C92.1 ICD-9 205.1 ICD-O: M9863/3 DiseasesDB 2659 MedlinePlus 000570 eMedicine med/371

Chronic Myeloid Leukemia News

Dacogen data presented on trial in seniors with acute myeloid leukemia (News-Medical-Net)

Eisai Corporation of North America has announced data from a Phase II trial evaluating a five-day dosing regimen of Dacogen(R) (decitabine for injection) in acute myeloid leukemia (AML), the most common form of leukemia.

Alfacell's ONCONASE And R-Amphinase Show Anti-Tumor Activity In Chronic Lymphocytic Leukemia And Acute Myeloblastic ...

Alfacell Corporation (Nasdaq: ACEL) announced that American Society of Hematology (ASH) annual meeting abstracts in Blood (2008 112: Abstract 4205 & 2008 112: Abstract 4010) report that ONCONASE (ranpirnase) and R-Amphinase (R-Amph) show anti-tumor activity in chronic lymphocytic leukemia (CLL) and

Dacogen Data On Phase II Clinical Trial In Elderly Patients With Acute Myeloid Leukemia ...

Eisai Corporation of North America today announced data from a Phase II trial evaluating a five-day dosing regimen of Dacogen® (decitabine for injection) in acute myeloid leukemia (AML), the most common form of leukemia.

Why Gleevec-type Drugs Control, But Do Not Eradicate, Leukemia

Researchers are closer to understanding why certain chronic myeloid leukemia mutations are not stopped by the revolutionary targeted cancer pill, Gleevec, or similar therapies in that drug family.

Two Studies Say Senior Citizens Can Take Acute Myeloid Leukemia Treatments

Dec. 9, 2008Although acute myeloid leukemia usually strikes when people are about age 65, these senior citizens have often been offered only supportive care because they are believed to be too weak to withstand treatment.

Chronic Myeloid Leukemia: Diagnosis and Treatment

Chronic myeloid leukemia (CML) has become a model in research and management among malignant disorders. Since the discovery of the presence of a unique and constant chromosomal abnormality slightly more than 40 years ago, substantial progress has been made in the understanding of the biology of the

Chronic Myeloid Leukemia: Current Application of Cytogenetics and Molecular Testing for Diagnosis and Treatment

Chronic myeloid leukemia provides an illustrative disease model for both molecular pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal stem cell disease caused by an acquired somatic mutation that fuses, through chromosomal translocation, the abl and bcr genes on

Imatinib-induced nail hyperpigmentation in chronic myeloid leukemia

Sir, Imatinib mesylate has revolutionized the treatment of chronic myeloid leukemia (CML) and has been recently approved as first-line treatment. Most of the patients receiving imatinib experience hematological or non-hematological side effects. Skin changes are the most common non-hematological

Oral agent shows promise for chronic myeloid leukemia.

SAN DIEGO - A new oral drug for patients with Gleevec-resistant chronic myeloid leukemia led to remission in 86% of patients in a phase I trial. Obviously we're excited by that, Charles L. Sawyers, M.D., said at a press briefing during the annual meeting of the American Society of Hematology. The

The chronic leukemias of myeloid origin.

Chronic leukemias of myeloid origin (CLMO) disorders are the second major category of chronic leukemias. The first major category of chronic leukemias, leukemias of lymphoid origin, was discussed in part one of this two-part series (see MLO, November 1998, p. 26). This group of neoplastic disorders